Joel Meyer

Joel Meyer

Truman and Nellie Semans/Alex Brown & Sons Associate Professor of Molecular Environmental Toxicology

DGS of UPEH program

Dr. Meyer studies the effects of toxic agents and stressors on human and wildlife health. He is particularly interested in understanding the mechanisms by which environmental agents cause DNA damage, the molecular processes that organisms employ to protect prevent and repair DNA damage, and genetic differences that may lead to increased or decreased sensitivity to DNA damage. Mitochondrial DNA damage and repair, as well as mitochondrial function in general, are a particular focus. He studies these effects in the nematode Caenorhabditis elegans, in cell culture, and collaboratively in other laboratory model organisms as well as in human populations in the USA and globally.

In The News


Luz, Anthony L., Tewodros R. Godebo, Dhaval P. Bhatt, Olga R. Ilkayeva, Laura L. Maurer, Matthew D. Hirschey, and Joel N. Meyer. “From the Cover: Arsenite Uncouples Mitochondrial Respiration and Induces a Warburg-like Effect in Caenorhabditis elegans..” Toxicol Sci 152, no. 2 (August 2016): 349–62.
González-Hunt, Claudia P., Maxwell C. K. Leung, Rakesh K. Bodhicharla, Madeline G. McKeever, Andrew E. Arrant, Kathleen M. Margillo, Ian T. Ryde, et al. “Exposure to mitochondrial genotoxins and dopaminergic neurodegeneration in Caenorhabditis elegans..” Plos One 9, no. 12 (January 2014).
Meyer, J. N., M. C. K. Leung, J. P. Rooney, A. Sendoel, M. O. Hengartner, G. E. Kisby, and A. S. Bess. “Mitochondria as a target of environmental toxicants.” Toxicological Sciences 134, no. 1 (2013): 1–17.
Bess, A. S., T. L. Crocker, I. T. Ryde, and J. N. Meyer. “Mitochondrial dynamics and autophagy aid in removal of persistent mitochondrial DNA damage in Caenorhabditis elegans.” Nucleic Acids Research 40, no. 16 (2012): 7916–31.

Recent Grants


ENVIRON 819: Mechanisms in Environmental Toxicology (ENVIRON 819: Mechanisms in Environmental Toxicology)
ENVIRON 102: Introduction to Environmental Sciences and Policy (ENVIRON 102: Introduction to Environmental Sciences and Policy)
ENVIRON 593: Independent Studies and Projects (ENVIRON 593: Independent Studies and Projects)
PHARM 394: Research Independent Study (PHARM 394: Research Independent Study)
ENVIRON 848S: Seminar in Toxicology (ENVIRON 848S: Seminar in Toxicology)

Contact Information

Box 90328
Durham, NC 27708-0328
A354 Lev Sci Res Ctr
Durham, NC 27708


Ph.D., Duke University (2003)
B.S., Juniata College (1992)

Additional Resources