Joel Meyer

Joel Meyer

Truman and Nellie Semans/Alex Brown & Sons Associate Professor of Molecular Environmental Toxicology

Director of Graduate Studies, ENV PhD program

Dr. Meyer studies the effects of toxic agents and stressors on human and wildlife health. He is particularly interested in understanding the mechanisms by which environmental agents cause DNA damage, the molecular processes that organisms employ to protect prevent and repair DNA damage, and genetic differences that may lead to increased or decreased sensitivity to DNA damage. Mitochondrial DNA damage and repair, as well as mitochondrial function in general, are a particular focus. He studies these effects in the nematode Caenorhabditis elegans, in cell culture, and collaboratively in other laboratory model organisms as well as in human populations in the USA and globally.

In The News

SELECTED PUBLICATIONS

Luz, AL, Godebo, TR, Bhatt, DP, Ilkayeva, OR, Maurer, LL, Hirschey, MD, and Meyer, JN. "From the Cover: Arsenite Uncouples Mitochondrial Respiration and Induces a Warburg-like Effect in Caenorhabditis elegans." Toxicological sciences : an official journal of the Society of Toxicology 152, no. 2 (August 2016): 349-362.
González-Hunt, CP, Leung, MCK, Bodhicharla, RK, McKeever, MG, Arrant, AE, Margillo, KM, Ryde, IT, Cyr, DD, Kosmaczewski, SG, Hammarlund, M, and Meyer, JN. "Exposure to mitochondrial genotoxins and dopaminergic neurodegeneration in Caenorhabditis elegans." PloS one 9, no. 12 (January 2014): e114459-.
Meyer, JN, Leung, MCK, Rooney, JP, Sendoel, A, Hengartner, MO, Kisby, GE, and Bess, AS. "Mitochondria as a target of environmental toxicants." Toxicological Sciences 134, no. 1 (2013): 1-17.
Bess, AS, Crocker, TL, Ryde, IT, and Meyer, JN. "Mitochondrial dynamics and autophagy aid in removal of persistent mitochondrial DNA damage in Caenorhabditis elegans." Nucleic Acids Research 40, no. 16 (2012): 7916-7931.
Meyer, JN, Leuthner, TC, and Luz, AL. "Mitochondrial fusion, fission, and mitochondrial toxicity." Toxicology (August 5, 2017).
Hartman, JH, Kozal, JS, Di Giulio, RT, and Meyer, JN. "Zebrafish have an ethanol-inducible hepatic 4-nitrophenol hydroxylase that is not CYP2E1-like." Environmental toxicology and pharmacology 54 (July 10, 2017): 142-145.
Luz, AL, Godebo, TR, Smith, LL, Leuthner, TC, Maurer, LL, and Meyer, JN. "Deficiencies in mitochondrial dynamics sensitize Caenorhabditis elegans to arsenite and other mitochondrial toxicants by reducing mitochondrial adaptability." Toxicology 387 (July 2017): 81-94.
Weinstein, JR, Asteria-Peñaloza, R, Diaz-Artiga, A, Davila, G, Hammond, SK, Ryde, IT, Meyer, JN, Benowitz, N, and Thompson, LM. "Exposure to polycyclic aromatic hydrocarbons and volatile organic compounds among recently pregnant rural Guatemalan women cooking and heating with solid fuels." International journal of hygiene and environmental health 220, no. 4 (June 2017): 726-735.

Courses

ENVIRON 819: Mechanisms in Environmental Toxicology (ENVIRON 819: Mechanisms in Environmental Toxicology)
ENVIRON 102: Introduction to Environmental Sciences and Policy (ENVIRON 102: Introduction to Environmental Sciences and Policy)
ENVIRON 593: Independent Studies and Projects (ENVIRON 593: Independent Studies and Projects)
ENVIRON 848S: Seminar in Toxicology (ENVIRON 848S: Seminar in Toxicology)
GLHLTH 795: Connections in Global Health: Interdisciplinary Team Projects (GLHLTH 795: Connections in Global Health: Interdisciplinary Team Projects)

Contact Information

Box 90328
Durham, NC 27708-0328
A354 Lev Sci Res Ctr
Durham, NC 27708

Education

Ph.D., Duke University (2003)
B.S., Juniata College (1992)

Additional Resources