Heather M. Stapleton

Heather M. Stapleton

Dan and Bunny Gabel Associate Professor of Environmental Ethics and Sustainable Environmental Management

Chair, EEH Program

Dr. Stapleton's research focuses on understanding the fate and transformation of organic contaminants in aquatic systems and in indoor environments. Her main focus has been on the bioaccumulation and biotransformation of brominated flame retardants, and specifically polybrominated diphenyl ethers,(PBDEs). Her current research projects explore the routes of human exposure to flame retardant chemicals and examine the way these compounds are photodegraded and metabolized using mass spectrometry to identify breakdown products/metabolites. She uses both in vivo techniques iwth fish, and in vitro techniques with cell cultures to examine metabolism of this varied class of chemicals. Also of interest to Dr. Stapleton is the study of the fate of PBDEs in the environment which may lead to bioaccumulation in aquatic systems and examining their bioavailability under different environmental conditions.

In The News


Bello, A, Carignan, CC, Xue, Y, Stapleton, HM, and Bello, D. "Exposure to organophosphate flame retardants in spray polyurethane foam applicators: Role of dermal exposure." Environment international 113 (April 2018): 55-65.
Frederiksen, M, Stapleton, HM, Vorkamp, K, Webster, TF, Jensen, NM, Sørensen, JA, Nielsen, F, Knudsen, LE, Sørensen, LS, Clausen, PA, and Nielsen, JB. "Dermal uptake and percutaneous penetration of organophosphate esters in a human skin ex vivo model." Chemosphere 197 (April 2018): 185-192.
Kassotis, CD, Kollitz, EM, Ferguson, PL, and Stapleton, HM. "Nonionic Ethoxylated Surfactants Induce Adipogenesis in 3T3-L1 Cells." Toxicological sciences : an official journal of the Society of Toxicology 162, no. 1 (March 2018): 124-136.
Holzem, RM, Gardner, CM, Stapleton, HM, and Gunsch, CK. "Using laboratory-generated biosolids to evaluate the microbial ecotoxicity of triclosan in a simulated land application scenario." Environmental science and pollution research international (February 6, 2018).

Recent Grants


ENVIRON 593: Independent Studies and Projects (ENVIRON 593: Independent Studies and Projects)
ENVIRON 898: Program Area Seminar (ENVIRON 898: Program Area Seminar)
ENVIRON 394: Research Independent Study (ENVIRON 394: Research Independent Study)
ENVIRON 780: Environmental Exposure Analysis (ENVIRON 780: Environmental Exposure Analysis)
ENVIRON 360: Environmental Chemistry and Toxicology (ENVIRON 360: Environmental Chemistry and Toxicology)

Contact Information

Box 90328
Durham, NC 27708-0328
9 Circuit Drive, Box 90328, LSRC Room A207
Durham, NC 27710


Ph.D., University of Maryland, College Park (2003)
M.S., University of Maryland, College Park (2000)
B.S., Long Island University Southhampton College (1997)

Additional Resources